Nichole Wang, DO

Nichole Wang, DO

Clinical Assistant Professor

Neonatology

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Lucile Packard Children's Hospital Stanford
725 Welch Road
Palo Alto, CA 94304
Fax: (650) 724-3243

Locations

Lucile Packard Children's Hospital Stanford

725 Welch Road

Palo Alto, CA 94304

Maps, Directions & Parking

Phone : (650) 497-8000

Fax : (650) 724-3243

Services

Neonatology

Work and Education

Professional Education

University of Northern Texas College of Osteopathic Medicine, Fort Worth, TX, 06/21/2013

Residency

Lucile Packard Children's Hospital at Stanford, Palo Alto, CA, 6/30/2016

Board Certifications

Pediatrics, American Board of Pediatrics, 2016

Languages

English

Publications

Changing Management of the Patent Ductus Arteriosus: Effect on Neonatal Outcomes and Resource Utilization. American journal of perinatology Chock, V. Y., Goel, V. V., Palma, J. P., Luh, T. M., Wang, N. A., Gaskari, S., Punn, R., Silverman, N. H., Benitz, W. E. 2017

Abstract

Objective This historical cohort study investigated how a shift toward a more conservative approach of awaiting spontaneous closure of the patent ductus arteriosus (PDA) in preterm infants has affected neonatal outcomes and resource utilization. Methods We retrospectively studied very low birth weight infants diagnosed with a PDA by echocardiogram (ECHO) in 2006-2008 (era 1), when medical or surgical PDA management was emphasized, to those born in 2010-2012 (era 2) when conservative PDA management was encouraged. Multiple regression analyses adjusted for gestational age were performed to assess differences in clinical outcomes and resource utilization between eras. Results More infants in era 2 (35/89, 39%) compared with era 1 (22/120, 18%) had conservative PDA management (p < 0.01). Despite no difference in surgical ligation rate, infants in era 2 had ligation later (median 24 vs. 8 days, p < 0.0001). There was no difference in clinical outcomes between eras, while number of ECHOs per patient was the only resource measure that increased in era 2 (median 3 vs. 2 ECHOs, p = 0.003). Conclusion In an era of more conservative PDA management, no increase in adverse clinical outcomes or significant change in resource utilization was found. Conservative PDA management may be a safe alternative for preterm infants.

View details for DOI 10.1055/s-0037-1601442

View details for PubMedID 28376547